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2281073 Martin D. Bootman; Michael J. Berridge; James W. Putney:
Calcium Signaling
  Preis:   € 25,00

Reihe: A Cold Spring Harbor Perspectives in Biology Collection, Einband: HArdcover
Auflage: 1.Auflage
Verlag: Cold Spring Harbor Laboratory Press New York
Erscheinungsdatum: 10/2011
Seiten: 400 pp. (approx.)
Abbildungen: illus. (71 color, 11 b/w),

ISBN-10: 0-87969-903-5   
ISBN-13: 978-0-87969-903-1

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Calcium ions play a critical role in signaling in a wide variety of tissues, including muscle, immune cells, neurons, the liver and oocytes. They can enter the cytoplasm from the extracellular environment or from intracellular stores and control the activity of numerous enzymes, other signaling molecules, transcription factors, and cytoskeletal components. Much is known about regulation of calcium fluxes, the channels and pumps that transport calcium between different compartments, cytosolic calcium buffers and sensors and how these produce distinct spatiotemporal calcium signals in different circumstances. The proposed book will cover these relatively well-established aspects of the field, together with newer work implicating calcium in the regulation of apoptosis during normal physiology and necrotic cell death in pathological conditions such as stroke and ischemia. The book has been edited by the father of the field (Berridge), two other renowned researchers (Putney and Tsien), and rising star and former protégé of Berridge (Bootman). It will include chapters by leaders in all aspects of calcium biology, promising to be the most comprehensive treatment of the subject yet.
Calcium signal generation/modulation and homeostasis

Calcium entry

1. Voltage-Gated Calcium Channels
William A. Catterall
2. The role of Transient Receptor Potential (TRP) Cation Channels in Ca2+ Signaling
Maarten Gees, Barbara Colsoul, and Bernd Nilius
3. Store-Operated Calcium Channels: New Perspectives on Mechanism and Function
Richard S. Lewis
4. mGluR1/TRPC3-mediated Synaptic Transmission and Calcium Signaling in Mammalian Central Neurons
Jana Hartmann, Horst A. Henning, and Arthur Konnerth

Calcium release

5. Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release
Johanna T. Lanner, Dimitra K. Georgiou, Aditya D. Joshi, and Susan L. Hamilton
6. IP3 receptors: Toward Understanding Their Activation
Colin W. Taylor and Stephen C. Tovey
7. NAADP Receptors
Antony Galione
8. Calcium Oscillations
Geneviève Dupont, Laurent Combettes, Gary S. Bird, and James W. Putney

Calcium buffers and pumps

9. Cytosolic “Ca2+ buffers”
Beat Schwaller
10. Organellar Calcium Buffers
Daniel Prins and Marek Michalak
11. The Plasma Membrane Ca2+ ATPase and the Plasma Membrane Sodium Calcium Exchanger Cooperate in the Regulation of Cell Calcium
Marisa Brini and Ernesto Carafoli
12. The Ca2+ Pumps of the Endoplasmic Reticulum and Golgi Apparatus
Ilse Vandecaetsbeek, Peter Vangheluwe, Luc Raeymaekers, Frank Wuytack, and Jo Vanoevelen

Functional Aspects of Calcium Signaling

Proteins mediating effects of calcium

13. The Diversity of Calcium Sensor Proteins in the Regulation of Neuronal Function
Hannah V. McCue, Lee P. Haynes, and Robert D. Burgoyne
14. Regulation by Ca2+-Signaling Pathways of Adenylyl Cyclases
Michelle L. Halls and Dermot M.F. Cooper
15. Protein Kinase C: The “Masters” of Calcium and Lipid
Peter Lipp and Gregor Reither

Physiological processes regulated by calcium

16. Ca2+ Signaling During Mammalian Fertilization: Requirements, Players, and Adaptations
Takuya Wakai, Veerle Vanderheyden, and Rafael A. Fissore
17. Calcium Signaling in Neuronal Development
Sheila S. Rosenberg and Nicholas C. Spitzer
18. Visualization of Ca2+ Signaling During Embryonic Skeletal Muscle Formation in Vertebrates
Sarah E. Webb and Andrew L. Miller
19. Calcium Signaling in Synapse-to-Nucleus Communication
Anna M. Hagenston and Hilmar Bading
20. Calcium Signaling in Cardiac Myocytes
Claire J. Fearnley, H. Llewelyn Roderick, and Martin D. Bootman
21. Calcium Signaling in Smooth Muscle
David C. Hill-Eubanks, Matthias E. Werner, Thomas J. Heppner, and Mark T. Nelson

Calcium in cell death and disease

22. Apoptosis and Autophagy: Decoding Calcium Signals that Mediate Life or Death
Michael W. Harr and Clark W. Distelhorst
23. Endoplasmic-Reticulum Calcium Depletion and Disease
Djalila Mekahli, Geert Bultynck, Jan B. Parys, Humbert De Smedt, and Ludwig Missiaen


Martin D. Bootman, The Babraham Institute;
Michael J. Berridge, The Babraham Institute;
James W. Putney, National Institutes of Health;
H. Llewelyn Roderick, The Babraham Institute
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