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2912983 Ferro-Novick, Susan; Rapoport, Tom A.; Schekman, Randy:
Endoplasmic Reticulum
  Preis:   € 69,80

Reihe: Perspective in Biology, Einband: Hardcover
Auflage: 1. Auflage
Verlag: Cold Spring Harbor Laboratory Press New York
Erscheinungsdatum: 02/2013
Seiten: 400 pp.(approx.)
Abbildungen: illus (60 4C, 10 B&W), index

ISBN-10: 1-936113-82-1   
ISBN-13: 978-1-936113-82-8


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Beschreibung
The endoplasmic reticulum (ER) is a critical cellular organelle. It is the first stage of the secretory pathway and contains numerous enzymes that facilitate correct folding and transport of proteins. This book discusses the structure and organization of the ER and its role in protein transport and quality control.
Inhalt
Contents

Preface
Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response
Brooke M. Gardner, David Pincus, Katja Gotthardt, Ciara M. Gallagher, and Peter Walter
Protein Folding Homeostasis in the Endoplasmic Reticulum and Nutritional Regulation
David Ron and Heather P. Harding
The Mammalian ERAD System
James A. Olzmann, Ron R. Kopito, and John C. Christianson
The ERAD Pathways of Budding Yeast
Guillaume Thibault and Davis T.W. Ng
Protein Folding in the Endoplasmic Reticulum
Ineke Braakman and Daniel N. Hebert
Disulfide Bond Formation in the Mammalian Endoplasmic Reticulum
Neil J. Bulleid
Endoplasmic Reticulum Structure and Interconnections with Organelles
Amber R. English and Gia K. Voeltz
Lipid Transport between the Endoplasmic Reticulum and Mitochondria
Vid V. Flis and Günther Daum
The Role of the Endoplasmic Reticulum in Peroxisome Biogenesis
Lazar Dimitrov, Sheung Kwan Lam, and Randy Schekman
How Viruses Use the Endoplasmic Reticulum for Entry, Replication, and Assembly
Takamasa Inoue and Billy Tsai
The Contribution of Systematic Approaches to Characterizing the Proteins and Functions of the Endoplasmic Reticulum
Maya Schuldiner and Jonathan S. Weissman
Cell Biology of the ER and the Golgi Apparatus through Proteomics
Jeffrey Smirle, Catherine E. Au, Michael Jain, Kurt Dejgaard, Tommy Nilsson, and John J. Bergeron
Nonvesicular Lipid Transfer from the Endoplasmic Reticulum
Sima Lev
Sphingolipid Homeostasis in the Endoplasmic Reticulum and Beyond
David K. Breslow
ER Targeting and Insertion of Tail-Anchored Membrane Proteins by the GET Pathway
Vladimir Denic, Volker Dötsch, and Irmgard Sinning
Protein Translocation across the Rough Endoplasmic Reticulum
Elisabet C. Mandon, Steven F. Truemen, and Reid Gilmore
N-linked Protein Glycosylation in the Endoplasmic Reticulum
Jörg Breitling and Markus Aebi
The Highly Conserved COPII Coat Complex Sorts Cargo from the ER and Targets it to the Golgi
Christopher Lord, Susan Ferro-Novick, and Elizabeth A. Miller
Functional Insights from Studies on the Structure of the Nuclear Pore and Coat Protein Complexes
Thomas Schwartz
Expanding Proteostasis by Membrane Trafficking Networks
Darren M. Hutt and William E. Balch
Retrograde Traffic from the Golgi to the ER (sp out)
Anne Spang

Zielgruppe/Leser
Cell Biology - Developmental Biology - Proteins and Proteomics - Cancer - Oncogenes
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