Inhalt
OVERVIEW
Tim Hunt
BIOCHEMICAL ERA
S. Rapoport; Detlef Doenecke and Peter Karlson; Frank Schlenk; Joseph S. Fruton
ORIGINS OF MOLECULAR BIOLOGY
G. Rickey Welch; Jan A. Witkowski; Seymour S. Cohen; Robert Olby
THE DOUBLE HELIX
Peter Karlson; Keith L. Manchester; Herbert Wilson; Anne Piper
REPLICATION
Frederic L. Holmes; J. Herbert Taylor; Stephen Cooper
DNA MOLECULES
Julius Marmur; Ed M. Southern; Bruno H. Zimm; Jacob Lebowitz
DNA, RNA, AND PROTEIN SYNTHESIS
Protein Synthesis: Hans–Jörg Rheinberger; Jean Brachet; Denis Thieffry and Richard M. Burian
Genetic Code: Marshall Nirenberg; Akira Kaji and Hideko Kaji
tRNA: Mahlon Hoagland; Bernard Weisblum; Brian F.C. Clark
mRNA: Elliot Volkin; Henry Harris; Klaus Scherrer; Jan A. Witkowski
Molecular Basis of Protein Synthesis: Norton D. Zinder; Masayasu Nomura; Jonathan R. Warner and Paul M. Knopf; B. Edward H. Maden
Central Dogma: Denis Thieffrey and Sahotra Sarkar
SEQUENCING
Soroya de Chadarevain; J. Gregor Sutcliffe
BIOCHEMISTRY AND MOLECULAR BIOLOGY
Sydney Brenner
Zielgruppe/Leser
Reviews
review: “This book is of potential interest for aficionados of the history of science, particularly relating to molecular biology, and selected chapters might be of value to scientists in training, or early in their career. Some of the chapters provide insights into the processes of scientific discovery, scientific competition and culture, and how new data and theories are rarely as simple and clearcut at the time of discovery as they are in retrospect...the best insights are provided by scientists who were struggling with research problems as trainees or early in their careers. Several of these accounts are true gems, clearly presenting the problems in the context of the state of knowledge, technology, and competing hypotheses of earlier times (now mostly discarded and forgotten). These stories describe thought processes, false leads, competition and feuds between research groups and disciplines, personalities, and courses of investigation leading to discoveries.”
—Clinical Chemistry
review: “The essays are often accompanied by photographs of the young participants at the time of their major contributions to this narrative, diagrams used at the time of publication, laboratory notebook entries with graphs and data, and an occasional cartoon. The styles vary from near review article to very introspective studies of proteins, competition, and the genesis of ideas in science. Most are enjoyable, and reading all 40 will give scientists a rich picture of what happened during the last 50 years of the 20th century, when molecular biology startled geneticists, biochemists, microbiologists, evolutionists, and physicians with surprising new insights or techniques pouring out of the journal pages in those very exciting decades. Many of the contributors are from Europe, and they are self–declared biochemists. It is good to see the different approaches and assumptions of these sometimes colliding and often cooperating groups who reshaped biology by digging into the cells, its organelles, and their chemical functions.”
—The Quarterly Review of Biology
Autoreninfo
Jan Witkowski, Cold Spring Harbor Laboratory
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CRISPR-Cas:
Budding Yeast
Learning and Memory
Conservation Science: Balancing the Needs of People and Nature
Introduction to Optical Microscopy
Organic Chemistry
CURRENT PROTOCOLS Wiley USA