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2281077 Frederic D. Bushman; Gary J. Nabel; Ronald Swanstrom:
HIV: From Biology to Prevention and Treatment
  Preis:   € 69,00

Reihe: A Cold Spring Harbor Perspectives in Biology Collection, Einband: Hardcover
Auflage: 1.Auflage
Verlag: Cold Spring Harbor Laboratory Press New York
Erscheinungsdatum: 12/2011
Seiten: 375 pp. (approx.)
Abbildungen: illus., index

ISBN-10: 1-936113-40-6   
ISBN-13: 978-1-936113-40-8

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The basic biology of the HIV virus provides a model for a more general understanding of retroviruses, and the worldwide epidemic of AIDS makes research into the disease process and potential therapies among the most critical in biomedical science. This book will explore work on the molecular biology of HIV, host-virus interactions, host immune responses, HIV transmission, as well as approaches to vaccine design, other prevention strategies, and current and potential therapies.

1. Origins of HIV and the AIDS Pandemic
Paul M. Sharp and Beatrice H. Hahn
2. Cell binding and entry
Craig B. Wilen, John C. Tilton, and Robert W. Doms
3. Reverse Transcription
Wei-Shau Hau and Stephen H. Hughes
4. Integration
Robert Craigie and Frederic D. Bushman
5. Transcriptional and Post-Transcriptional Regulation of HIV-1 Gene Expression
Jonathan Karn and C. Martin Stoltzfus
6. Assembly, Budding, and Release
Wesley I. Sundquist
7. Restriction Factors
Michael H. Malim and Paul D. Bieniasz
8. HIV transmission
Eric Hunter
9. HIV Pathogenesis — The Virus
John Coffin and Ronald Swanstrom
10. HIV Pathogenesis — The Host
Andrew A. Lackner, Michael M. Lederman, and Benigno Rodriguez
11. The Antibody Response Against HIV-1
Julie Overbaugh and Lynn Morris
12. The T-cell response against HIV
Bruce Walker
13. Natural killer cells in protection against HIV disease
Mary Carrington and Galit Alter
14. HIV Latency
Robert F. Siliciano and Warner C. Greene
15. Neuroaids
Francisco Gonzalez-Scarano
16. Nonpathogenic Simian Immunodeficiency Virus Infections
Nichole R. Klatt, Guido Silvestri, and Vanessa Hirsch
17. HIV-1 Antiretroviral Drug Therapy
Eric Arts and Daria Hazuda
18. Novel Cell and Gene Therapies for HIV
James A. Hoxie and Carl H. June
19. The HIV Epidemic: The Southern Hemisphere
Carolyn Williamson and Yiming Shao
20. The HIV Epidemic: High-Income Nations
Sten H. Vermund and Andrew Leigh-Brown
21. Host Selection Shaping Viral Evolution
Amalio Telenti
22. Vaccine Design for CTL Responses
Richard A. Koup and Daniel C. Douek
23. Rational Design of Vaccines to Elicit Broadly Neutralizing Antibodies to HIV-1
Peter D. Kwong, John R. Mascola, Gary J. Nabel
24. Lessons in Non-Human Primate Models for AIDS Vaccine Research: From Minefields to Milestones
Jeffrey D. Lifson and Nancy L. Haigwood
25. Human Immunodeficiency Virus Vaccine Trials
Robert J. O’Connell, Jerome H. Kim, Lawrence Corey, and Nelson L. Michael
26. Microbicides: Topical Prevention Against HIV
Robin J. Shattock and Zeda Rosenberg
27. Pre-Exposure Prophalyxis
Walid Heneine
28. Behavioral and Biomedical Combination Strategies for HIV Prevention
Thomas Quinn, Linda-Gail Bekker, and Chris Beyrer


Frederic D. Bushman, University of Pennsylvania School of Medicine;
Gary J. Nabel, NIAID, National Institutes of Health; Ronald Swanstrom, University of North Carolina at Chapel Hill
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