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1921415 Fred H. Gage; G. Kempermann; H. Song:
Adult Neurogenesis
  Preis:   € 0,00

Einband: Hardcover
Auflage: 1. Auflage
Verlag: Cold Spring Harbor Laboratory Press
Erscheinungsdatum: 12/2007
Seiten: 600 pp
Abbildungen: Illustrations, index

ISBN-10: 0-87969-784-9   
ISBN-13: 9780879697846


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Beschreibung
The idea that the adult brain of mammals can generate new neurons has only recently been accepted by the scientific community, and research in this exciting area is now in full swing. Bringing together leading researchers in the field of adult neurogenesis, the 30 chapters in this monograph provide a valuable overview of this emerging field and lay the groundwork for future studies. Adult Neurogenesis includes discussions on neural stem cell biology; methods and models for studying adult neurogenesis; physiological and molecular processes and their control; related neurological diseases; and comparisons of neurogenesis in humans, birds, fish, and invertebrates. It will be of interest to all researchers in neurobiology as well as those in the medical field, as it has implications for understanding depression, epilepsy, and other psychiatric disorders.
Inhalt
Contents

1. Adult Neurogenesis: A Prologue
F.H. Gage, H. Song, and G. Kempermann

METHODS
In vivo approaches
2. Numerology of Neurogenesis: Characterizing the Cell Cycle of Neurostem Cells
R.S. Nowakowski and N.L. Hayes
3. Detection and Phenotypic Characterization of Adult Neurogenesis
H.G. Kuhn and D.A. Peterson
4. Evolving Methods for the Labeling and Mutation of Postnatal Neuronal Precursor Cells: A Critical Review
J.J. Breunig, J. D. Macklis, and P.R. Rakic
5. The Use of Reporter Mouse Lines to Study Adult Neurogenesis
G. Enikolopov and L. Overstreet-Wadiche
6. Retrovirus-mediated Cell Labeling
C. Zhao
In vitro approaches
7. Neurospheres
I. Singec and A. Quiñones-Hinojosa
8. Monolayer Cultures of Neuronal Stem/Progenitor Cells
J. Ray

BASIC PROCESSES
9. Neurogenesis in the Adult Hippocampus
G. Kempermann, H. Song, and F.H. Gage
10. Adult Subventricular Zone and Olfactory Bulb Neurogenesis
D.A. Lim, Y.-C. Huang, and A. Alvarez-Buylla
11. Neurogenic Niches in the Adult Mammalian Brain
D.K. Ma, G.-l. Ming, F.H. Gage, and H. Song

MOLECULAR AND PHYSIOLOGICAL MECHANISMS
12. Adult Neurogenesis: Similarities and Differences in Stem Cell Fate, Proliferation, Migration, and Differentiation in Distinct Forebrain Regions
D.C. Lie and M. Götz
13. Proneuronal Genes Drive Neurogenesis on the Road from Development to Adulthood
E.T. Buchen and S.J. Pleasure
14. The Balance of Trophic Support and Cell Death in Adult Neurogenesis
H.G. Kuhn
15. Maturation and Functional Integration of New Granule Cells into the Adult Hippocampus
J. Bischofberger and A.F. Schinder

REGULATION
16. Genetics and Epigenetics in Adult Neurogenesis
J. Hsieh and J.W. Schneider
17. Activity Dependency and Aging in the Regulation of Adult Neurogenesis
G. Kempermann
18. Regulation of Hippocampal Neurogenesis by Systemic Factors Including Stress, Glucocorticoids, Sleep, and Inflammation
P.J. Lucassen, C.A. Oomen, A.-M. van Dam, and B. Czéh
19. Regulation of Adult Neurogenesis by Neurotransmitters
M.-H. Jang, H. Song, and G.-l Ming

FUNCTIONAL SIGNIFICANCE
20. Adult Neurogenesis in the Olfactory Bulb
P.-M. Lledo
21. Neurogenesis and Hippocampal Memory System
D.N. Abrous and J.M. Wojtowicz
22. Computational Modeling of Adult Neurogenesis
J.B. Aimone and L. Wiskott

NEUROLOGICAL DISEASES
23. Hippocampal Neurogenesis: Depression and Antidepressant Responses
A. Sahay, R. Hen, and R.S. Duman
24. Adult Neurogenesis in Neurodegenerative Diseases
P. Brundin, J. Winkler, and E. Masliah
25. Epilepsy and Adult Neurogenesis
S. Jessberger and J.M. Parent
26. Neurogenesis Following Stroke Affecting the Adult Brain
O. Lindvall and Z. Kokaia

COMPARATIVE NEUROGENESIS
27. Adult Neurogenesis in Teleost Fish
G.K.H. Zupanc
28. Neurogenesis in the Adult Songbird: A Model for Inducible Striatal Neuronal Addition
S.A. Goldman
29. Adult Human Neurogenesis: A Response to Cell Loss and New Circuitry Requirements
M.A. Curtis, P.S. Eriksson, and R.L.M. Faull
30. Adult Hippocampal Neurogenesis in Natural Populations of Mammals
I. Amrein, H.-P. Lipp, R. Boonstra, and J.M. Wojtowicz
Index

Autoreninfo
Fred H. Gage, The Salk Institute for Biological Studies, San Diego, California; Gerd Kempermann, Center for Regenerative Therapies, Dresden, Germany; Hongjun Song, Johns Hopkins School of Medicine, Baltimore, Maryland

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