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3329199 Kaufmann, H. E.; Rubin, Eric; Zumla, Ali:
Tuberculosis
  Preis:   € 115,00

Band: Perspectives in Medicine, Einband: Hardcover
Auflage: 1.Auflage
Verlag: Cold Spring Harbor Laboratory Press New York
Erscheinungsdatum: 11/2014
Seiten: 350 pp. (approx.),
Abbildungen: illus., index

ISBN-10: 1-62182-073-4   
ISBN-13: 978-1-621820-73-4


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Beschreibung
Tuberculosis is a global health burden that is endemic in many areas of the developing world and a particular problem in HIV infection. This book examines the mycobacterium that causes the disease, the effects on the host, and ongoing vaccination and treatment strategies.
Inhalt
Contents
(preliminary) Section 1. Clinical Tuberculosis1. Global Epidemiology of TuberculosisPhilippe Glaziou, Charalambos Sismanidis, Katherine Floyd, and Mario Raviglione2. Advances in Diagnostic Assays for TuberculosisSteven D. Lawn3. Imaging in TuberculosisJamshed B. Bomanji, Narainder Gupta, Parveen Gulati, and Chandan J. Das4. TB Treatment and Drug RegimensGiovanni Sotgiu, Rosella Centis, Lia D’ambrosio, and Giovanni Battista Migliori5. Diagnosis and Management of Latent Tuberculosis InfectionLaura Muñoz, Helen R. Stagg, and Ibrahim Abubakar6. Clinical Aspects of Adult TuberculosisRobert Loddenkemper, Marc Lipman, and Alimuddin Zumla7. Tuberculosis in ChildrenBen J. Marais and H. Simon Schaaf8. Multidrug-Resistant TB and Extensively Drug-Resistant TBKwonjune J. Seung, Salmaan Keshavjee, and Michael L. Rich9. Tuberculosis and HIV Co-InfectionJudith Bruchfeld, Margarida Correia-Neves, and Gunilla Källenius10. Tuberculosis Co-Morbidity with Communicable and Non-Communicable DiseasesMatthew Bates, Ben J. Marais, and Alimuddin Zumla11. Infection Control and TuberculosisEdward Nardell Section 2. Vaccines, Immunology, Host Cells, and Biomarkers12. Innate and Adaptive Cellular Immune Responses to Mycobacterium tuberculosis InfectionKatrin D. Mayer-Barber and Daniel L. Barber13. Role of B Cells and Antibodies in the Acquired Immunity against Mycobacterium tuberculosisJacqueline M. Achkar, John Chan, and Arturo Casadevall14. Antigens for CD4 and CD8 T Cells in TuberculosisCecilia S. Lindestam Arlehamn, David Lewinsohn, Alessandro Sette, and Deborah Lewinsohn15. Non-Classical T Cells and Their Antigens in TuberculosisGennaro De Libero, Amit Singhai, Marco Lepore, and Lucia Mori16. Autophagy in TuberculosisVojo Deretic17. Immunity and Immunopathology in the Tuberculous GranulomaAntonio J. Pagán and Lalita Ramakrishnan18. Cell-Autonomous Effector Mechanisms Against Mycobacterium tuberculosisJohn D. MacMicking19. Clinical Immunology and Multiplex Biomarkers of Human TuberculosisGerhard Walzl, Mariëlle C. Haks, Simone A. Joosten, Léanie Kleynhans, Katharina Ronacher, and Tom H.M. Ottenhoff20. Novel Vaccination Strategies Against TuberculosisPeter Andersen and Stefan H.E. Kaufmann21. Toward a Unified Biosignature for TuberculosisJeroen Maertzdorf, Stefan H.E. Kaufmann, and January Weiner III22. Manipulaiton of the Mononuclear Phagocyte System by Mycobacterium tuberculosisGeanncarlo Lugo-Villarino and Olivier Neyrolles23. Mouse Model of TuberculosisAndrea M. Cooper24. Modeling Tuberculosis in Non-Human PrimatesCharles A. Scanga and JoAnne L. Flynn25. Animal Models of Tuberculosis: Guinea PigsSimon Clark, Yper Hall, and Ann Williams26. Animal Models of Tuberculosis: ZebrafishLisanne M. van Leeuwen, Astrid M. van der Sar, and Wilbert Bitter Section 3.27. Mycobacterial GrowthIria Uhia, Kerstin J. Williams, Vahid Shahrezaei, and Brian D. Robertson28. The Mycobacterial Cell Envelope—LipidsMary Jackson29. The Mycobacterial Cell Wall—Peptidoglycan and ArabinogalactanLuke J. Alderwick, James Harrison, Georgina S. Lloyd, and Helen L. Birch30. Mycobacterium tuberculosis MetabolismDigby F. Warner31. Genetic Approaches to Facilitate Antibacterial Drug DevelopmentDirk Schnappinger32. TB Drug Development: History and Evolution of the Mechanism-Based ParadigmSumit Chakraborty and Kyu Y. Rhee33. The TB Drug Discovery and Development Pipeline and Emerging Drug TargetsKhisimuzi Mdluli, Takushi Kaneko, and Anna Upton34. Pharmacologic Considerations in Use and Development of Anti-Tuberculosis DrugsGeraint Davies35. Diversity and Evolution of Mycobacterium tuberculosis: Moving to Whole Genome-based ApproachesStefan Niemann and Philip Supply36. Host-Directed Therapies for TuberculosisDavid M. Tobin37. Comparative Genomics of Mycobacteria: Some Answers, Yet More New QuestionsMarcel A. Behr38. Interaction of Mycobacterium tuberculosis with Host Cell Death PathwaysLalitha Srinivasan, Sarah Ahlbrand, and Volker BrikenIndex

Zielgruppe/Leser
Inefektionskrankheiten, Mikrobiologie
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