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2187584 Grodzicker, Terri; Spector, David; Stewart, David:
Nuclear Organization and Function(Cold Spring Harbor Symposia on Quantitative Biology LXXV)
  Preis:   € 36,00

Reihe: Symposia on Quantitative Biology, Band: 75, Einband: Paperback
Verlag: Cold Spring Harbor Laboratory Press
Erscheinungsdatum: 06/2011
Seiten: 650 S.
Abbildungen: illus., indexes

ISBN-10: 1-936113-08-2   
ISBN-13: 9781-936113-08-8


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Beschreibung
This volume is based on presentations by the world-renowned investigators who gathered at the 75th annual Cold Spring Harbor Symposium on Quantitative Biology to discuss the organization and function of the cell nucleus. It reviews the latest advances in research into nuclear structure, the organization of the genome within the nucleus, and spatiotemporal coordination of nuclear processes. The topics examined include nuclear domains, chromatin organization, transcription and RNA processing, DNA replication, nuclear reprogramming, and epigenetics. Cancer, premature aging syndromes, and other diseases that may be associated with altered nuclear organization are also covered.
Inhalt
(preliminary)
Foreword
INTRODUCTION
John B. Gurdon, Rob Martienssen, Barbara J. Meyer, and Gunter Blobel

CHROMATIN MODIFICATIONS AND GENE EXPRESSION
John T. Lis, Danny Reinberg, Shelley Berger, C. David Allis, Steven Henikoff, Robert E. Kingston, and Gary Felsenfeld

DNA REPLICATION AND GENOME INTEGRITY
John Diffley, David M. Gilbert, Geneviève Almouzni, Bruce Stillman, Titia de Lange, Camilla Sjögren, and Craig L. Peterson

REPROGRAMMING AND DIFFERENTIATION
Rudolf Jaenisch, Azim Surani, Ken Zaret, Richard A. Young, Huck H. Ng, D.P. Bazett-Jones, and Tom Misteli

RNA BIOLOGY
Joseph G. Gall, Joan A. Steitz, Ramin Shiekhattar, Edith Heard, Jeanne B. Lawrence, and Sui Huang

CHROMOSOME STRUCTURE AND MITOSIS
Kim Nasmyth, Luis Aragon, Stephen C. Harrison, Don W. Cleveland, Yoshinori Watanabe, Tim Stearns, and William C. Earnshaw

HETEROCHROMATIN FORMATION AND GENE SILENCING
Shiv I. Grewal, Robin C. Allshire, Craig S. Pikaard, Nicholas J. Proudfoot, and Angelika Amon

TRANSCRIPTION MEETS RNA PROCESSING
Stephen Buratowski, Alberto R. Kornblihtt, Pamela A. Silver, A. Gregory Matera, Robert H. Singer, and Lynne E. Maquat

NUCLEAR PERIPHERY
Bas van Steensel, Robert D. Goldman, Roland Foisner, Susan M. Gasser, Michael P. Rout, and Martin W. Hetzer

CHROMATIN STRUCTURE AND ORGANIZATION
Daniela Rhodes, Andrew S. Belmont, Thomas Cremer, Rolf Ohlsson, Peter Fraser, and David L. Spector

GENOME REGULATION
Wendy Bickmore, Giacomo Cavalli, Ingrid Grummt, and Stephen B. Baylin

SUMMARY
Steven Henikoff

Author Index

Zielgruppe/Leser
Zellbiologie
Genetik
Onkologie
Molekularbiologie

Autoreninfo
Terri Grodzicker, Cold Spring Harbor Laboratory; David Spector, Cold Spring Harbor Laboratory; David Stewart, Cold Spring Harbor Laboratory; Bruce Stillman, Cold Spring Harbor Laboratory
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