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2281061 Simons, Kai:
The Biology of Lipids: Trafficking, Regulation, and Function
  Preis:   € 25,00

Einband: Hardcover
Auflage: 1.Auflage
Verlag: Cold Spring Harbor Laboratory Press New York
Erscheinungsdatum: 2011
Seiten: 334 pp
Abbildungen: illus. (45 color, 33 b/w), index

ISBN-10: 1-936113-39-2   
ISBN-13: 9781936113392


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Beschreibung
As the major structural component of cell membranes, lipids not only serve as barriers but also play active roles in cellular function. In this volume, contributors explore the synthesis, metabolism, and distribution of lipid species in the cell; the composition of lipid rafts and their roles in protein trafficking and signaling; and the biophysical behavior of lipids and membranes.
Inhalt
Contents

Membrane Organization and Lipid Rafts
Kai Simons and Julio L. Sampaio
Shotgun Lipidomics on High Resolution Mass Spectrometers
Dominik Schwudke, Kai Schuhmann, Ronny Herzog, Stefan R. Bornstein, and Andrej Shevchenko
Model Answers to Lipid Membrane Questions
Ole G. Mouritsen
Phase Separation in Lipid Membranes
Frederick A. Heberle and Gerald W. Feigenson
Lipid Polymorphisms and Membrane Shape
Vadim A. Frolov, Anna V. Shnyrova, and Joshua Zimmerberg
Curvature-Driven Lipid Sorting in Biomembranes
Andrew Callan-Jones, Benoit Sorre, and Patricia Bassereau
Lipid Simulations: A Perspective on Lipids in Action
Ilpo Vattulainen and Tomasz Rog
Fluorescence Techniques to Study Lipid Dynamics
Erdinc Sezgin and Petra Schwille
Dynamic Transbilayer Lipid Asymmetry
Gerrit van Meer
Glycosphingolipid Functions
Clifford A. Lingwood
Regulation of Cholesterol and Fatty Acid Synthesis
Jin Ye and Russell A. DeBose-Boyd
Distribution and Functions of Sterols and Sphingolipids
J. Thomas Hannich, Kyohei Umebayashi, and Howard Riezman
Phosphoinositides in Cell Architecture
Annette Shewan, Dennis J. Eastburn, and Keith Mostov
Specificity of Intramembrane Protein–Lipid Interactions
Francesc-Xabier Contreras, Andreas Max Ernst, Felix Wieland, and Britta Brügger
Synthesis and Biosynthetic Trafficking of Membrane Lipids
Tomas Blom, Pentti Somerharju, and Elina Ikonen
Lipid-Mediated Endocytosis
Helge Ewers and Ari Helenius
Not Just Fat: The Structure and Function of the Lipid Droplet
Toyoshi Fujimoto and Robert G. Parton
Lysosomal Lipid Storage Diseases
Heike Schulze and Konrad Sandhoff
Role of Lipids in Virus Replication
Maier Lorizate and Hans-Georg Kräusslich
Index

Autoreninfo
Kai Simons, Max Planck Institute of Molecular Cell Biology and Genetics
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